Alpha-virus Research using a Generic primer assay

Serial Dilutions a, b, c, d, e, f, g, …

Computer-aided Structure prediction of Bluetongue Virus coat protein VP2 assisted by Optimized Potential for Liquid Simulations(OPLS).

Bluetongue illness at present noticeable to the World Organization for Animal Health (OIE); causes huge financial losses on account of fast deteriorate commerce related to bluetongue outbreaks and excessive mortality and morbidity.The capsid coat protein of Bluetongue virus(BTV)VP2 is answerable for BTV transmission by the Culicoides vector to vertebrate hosts throughout blood feeding.

7 polypeptides have been discovered to be current within the capsid of the BTV, 4 of that are main and three are minor parts. Besides, VP2 is answerable for BTV entry into permissive cells and therefore performs a serious function in illness development.

However, its mechanism of motion just isn’t recognized until date.The current investigation aimed to foretell the 3D construction of Viral Protein 2 of bluetongue virus adopted by Structure validation, Molecular Dynamics simulation and lively website prediction.The In silico method offers a platform for figuring out the construction of the VP2 protein. The 3D construction of VP2 protein was constructed utilizing a Python-based Computational algorithm. The templates had been recognized utilizing Smith waterman’s Local alignment. The VP2 protein construction validated utilizing PROCHECK and offered utilizing Ramachandran plots.

Molecular Dynamics Simulation (MDS) research had been carried out utilizing an educational software program Desmond, Schrodinger dynamics for figuring out the steadiness of mannequin protein. The Ligand – Binding website was predicted by a homology looking out by construction comparability and protein-protein in networks evaluation, to reveals their stability and inhibition mechanism adopted by lively website identification.

The secondary construction of the mannequin concluded that the mannequin incorporates 220 Alpha Helix atoms, 403 10Helix, 151 Beta sheets, 134 coils and 424 turns whereas the 3D construction of Viral Protein 2 of BTV discovered to have 15774 complete atoms within the construction.961 amino acids had been discovered the ultimate mannequin.

EIF4E
MBS8564102-01mLAF405L 0.1mL(AF405L)
EUR 565

EIF4E
MBS8564102-01mLAF405S 0.1mL(AF405S)
EUR 565

EIF4E
MBS8564102-01mLAF610 0.1mL(AF610)
EUR 565

EIF4E
MBS8564102-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E
MBS8564102-02mL 0.2mL
EUR 345

EIF4E
pro-530 2µg
EUR 60
Description: Recombinant Human Eukaryotic Translation Initiation Factor 4E

eIF4E Antibody
ABF6110 100 ug
EUR 525.6

EIF4E Antibody
ABD6885 100 ug
EUR 525.6

Eif4e antibody
70R-9620 50 ug
EUR 467
Description: Affinity purified rabbit polyclonal Eif4e antibody

EIF4E antibody
70R-4682 50 ug
EUR 467
Description: Rabbit polyclonal EIF4E antibody raised against the C terminal of EIF4E

EIF4E antibody
70R-49697 100 ul
EUR 242
Description: Purified Polyclonal EIF4E antibody

eIF4E antibody
20R-2073 50 ug
EUR 269
Description: Rabbit polyclonal eIF4E antibody

eIF4E antibody
20R-2389 50 ug
EUR 269
Description: Rabbit polyclonal eIF4E antibody

EIF4E antibody
10R-3955 100 ul
EUR 709
Description: Mouse monoclonal EIF4E antibody

EIF4E antibody
10R-3956 100 ul
EUR 709
Description: Mouse monoclonal EIF4E antibody

EIF4E antibody
10R-3957 100 ul
EUR 709
Description: Mouse monoclonal EIF4E antibody

EIF4E antibody
10R-6905 100 ul
EUR 709
Description: Mouse monoclonal EIF4E antibody

EIF4E antibody
10R-11030 100 ug
EUR 344
Description: Mouse monoclonal EIF4E antibody

EIF4E Antibody
32632-100ul 100ul
EUR 302.4

EIF4E Antibody
1-CSB-PA002308
  • Ask for price
  • Ask for price
  • 50ug
  • 100ug
Description: A polyclonal antibody against EIF4E. Recognizes EIF4E from Human, Mouse, Rat, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

EIF4E Antibody
1-CSB-PA007556GA01HU
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  • 50ul
  • 150ul
Description: A polyclonal antibody against EIF4E. Recognizes EIF4E from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF

EIF4E Antibody
1-CSB-PA007556LA01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against EIF4E. Recognizes EIF4E from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

eIF4E Antibody
B7067-100ul 100μl
EUR 217
Description: eIF4E Rabbit Polyclonal Antibody

eIF4E Antibody
B7067-50ul 50μl
EUR 143.5
Description: eIF4E Rabbit Polyclonal Antibody

eIF4E Antibody
AF6110 200ul
EUR 420

eIF4E Antibody
AF6110-100ul 100ul
EUR 168
Description: WB,IHC,IF/ICC,ELISA(peptide)

eIF4E Antibody
AF6110-200ul 200ul
EUR 210
Description: WB,IHC,IF/ICC,ELISA(peptide)

eIF4E Antibody
AF7702 200ul
EUR 540

eIF4E Antibody
AF7702-100ul 100ul
EUR 210
Description: WB,ELISA(peptide)

eIF4E Antibody
AF7702-200ul 200ul
EUR 270
Description: WB,ELISA(peptide)

eIF4E Antibody
AF7702-50ul 50ul
EUR 150
Description: WB,ELISA(peptide)

EIF4E Antibody
DF6885 200ul
EUR 420

EIF4E Antibody
DF6885-100ul 100ul
EUR 168
Description: WB,IHC,ELISA(peptide)

EIF4E Antibody
DF6885-200ul 200ul
EUR 210
Description: WB,IHC,ELISA(peptide)

EIF4E Antibody
BF0279 200ul
EUR 540

EIF4E Antibody
BF0279-100ul 100ul
EUR 210
Description: WB,IHC,IF/ICC,ELISA,FACS

EIF4E Antibody
BF0279-200ul 200ul
EUR 270
Description: WB,IHC,IF/ICC,ELISA,FACS

EIF4E Antibody
BF0279-50ul 50ul
EUR 150
Description: WB,IHC,IF/ICC,ELISA,FACS

eIF4E Antibody
AF6741 100ul
EUR 420

eIF4E Antibody
AF6741-100ul 100ul
EUR 168
Description: WB,IF/ICC,ELISA(peptide)

eIF4E Antibody
AF6741-200ul 200ul
EUR 210
Description: WB,IF/ICC,ELISA(peptide)

EIF4E Antibody
E45M22110G-1 100 ul
EUR 395

EIF4E Antibody
E45M22110G-4 50 ul
EUR 295

EIF4E Antibody
E92162 100ul
EUR 255
Description: Available in various conjugation types.

EIF4E Antibody
E300116 100ug/200ul
EUR 275
Description: Available in various conjugation types.

EIF4E Antibody
E312256 200ul
EUR 275
Description: Available in various conjugation types.

EIF4E Antibody
E38PA1378 100ul
EUR 225
Description: Available in various conjugation types.

eIF4E Antibody
E2220030 100ug
EUR 225
Description: Available in various conjugation types.

eIF4E Antibody
E18-6110-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

eIF4E Antibody
E18-6110-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

EIF4E Antibody
E19-6885 100μg/100μl
EUR 225
Description: Available in various conjugation types.

EIF4E Antibody
E10-30189 100μg/100μl
EUR 225
Description: Available in various conjugation types.

EIF4E Antibody
GWB-MN417C 50ug Ask for price

Eif4e Antibody
GWB-MV426C 50ug Ask for price

EIF4E antibody
MBS5309464-01mL 0.1mL
EUR 1095

EIF4E antibody
MBS5309464-5x01mL 5x0.1mL
EUR 4770

eIF4E antibody
MBS5309586-005mg 0.05mg
EUR 485

eIF4E antibody
MBS5309586-5x005mg 5x0.05mg
EUR 2045

eIF4E antibody
MBS5309768-005mg 0.05mg
EUR 485

eIF4E antibody
MBS5309768-5x005mg 5x0.05mg
EUR 2045

EIF4E Antibody
MBS5314317-01mL 0.1mL
EUR 470

EIF4E Antibody
MBS5314317-5x01mL 5x0.1mL
EUR 1955

EIF4E Antibody
MBS2523706-006mL 0.06mL
EUR 190

EIF4E Antibody
MBS2523706-012mL 0.12mL
EUR 265

EIF4E Antibody
MBS2523706-02mL 0.2mL
EUR 415

EIF4E Antibody
MBS2523706-5x02mL 5x0.2mL
EUR 1835

EIF4E antibody
MBS830639-01mL 0.1mL
EUR 1095

EIF4E antibody
MBS830639-5x01mL 5x0.1mL
EUR 4770

EIF4E Antibody
MBS7048089-005mg 0.05mg
EUR 190

EIF4E Antibody
MBS7048089-01mg 0.1mg
EUR 270

EIF4E Antibody
MBS7048089-5x01mg 5x0.1mg
EUR 1205

EIF4E Antibody
MBS7116282-005mg 0.05mg
EUR 150

EIF4E Antibody
MBS7116282-01mg 0.1mg
EUR 190

EIF4E Antibody
MBS7116282-5x01mg 5x0.1mg
EUR 845

EIF4E Antibody
MBS850484-01mg 0.1mg
EUR 305

EIF4E Antibody
MBS850484-01mLAF405L 0.1mL(AF405L)
EUR 565

EIF4E Antibody
MBS850484-01mLAF405S 0.1mL(AF405S)
EUR 565

EIF4E Antibody
MBS850484-01mLAF610 0.1mL(AF610)
EUR 565

EIF4E Antibody
MBS850484-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E Antibody
MBS8516355-01mg 0.1mg
EUR 305

EIF4E Antibody
MBS8516355-01mLAF405L 0.1mL(AF405L)
EUR 465

EIF4E Antibody
MBS8516355-01mLAF405S 0.1mL(AF405S)
EUR 465

EIF4E Antibody
MBS8516355-01mLAF610 0.1mL(AF610)
EUR 465

EIF4E Antibody
MBS8516355-01mLAF635 0.1mL(AF635)
EUR 465

eIF4E Antibody
MBS8512196-005mg 0.05mg
EUR 235

eIF4E Antibody
MBS8512196-01mg 0.1mg
EUR 305

eIF4E Antibody
MBS8512196-01mLAF405M 0.1mL(AF405M)
EUR 465

eIF4E Antibody
MBS8512196-01mLAF546 0.1mL(AF546)
EUR 465

eIF4E Antibody
MBS8512196-01mLAF750 0.1mL(AF750)
EUR 465

eIF4E Antibody
MBS8500983-01mg 0.1mg
EUR 305

eIF4E Antibody
MBS8500983-01mLAF405L 0.1mL(AF405L)
EUR 565

eIF4E Antibody
MBS8500983-01mLAF405S 0.1mL(AF405S)
EUR 565

eIF4E Antibody
MBS8500983-01mLAF610 0.1mL(AF610)
EUR 565

eIF4E Antibody
MBS8500983-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E Antibody
MBS8501121-01mL 0.1mL
EUR 325

EIF4E Antibody
MBS8501121-01mLAF405L 0.1mL(AF405L)
EUR 565

EIF4E Antibody
MBS8501121-01mLAF405S 0.1mL(AF405S)
EUR 565

EIF4E Antibody
MBS8501121-01mLAF610 0.1mL(AF610)
EUR 565

EIF4E Antibody
MBS8501121-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E antibody
MBS831539-01mL 0.1mL
EUR 1095

EIF4E antibody
MBS831539-5x01mL 5x0.1mL
EUR 4770

EIF4E antibody
MBS831886-01mL 0.1mL
EUR 1095

EIF4E antibody
MBS831886-5x01mL 5x0.1mL
EUR 4770

EIF4E Antibody
MBS9207253-008mL 0.08mL
EUR 210

EIF4E Antibody
MBS9207253-04mL 0.4mL
EUR 430

EIF4E Antibody
MBS9207253-5x04mL 5x0.4mL
EUR 1910

EIF4E Antibody
MBS9200663-008mL 0.08mL
EUR 210

EIF4E Antibody
MBS9200663-04mL 0.4mL
EUR 430

EIF4E Antibody
MBS9200663-5x04mL 5x0.4mL
EUR 1910

EIF4E Antibody
MBS859292-01mg 0.1mg
EUR 345

EIF4E Antibody
MBS859292-01mLAF405L 0.1mL(AF405L)
EUR 565

EIF4E Antibody
MBS859292-01mLAF405S 0.1mL(AF405S)
EUR 565

EIF4E Antibody
MBS859292-01mLAF610 0.1mL(AF610)
EUR 565

EIF4E Antibody
MBS859292-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E Antibody
MBS8580548-01mL 0.1mL
EUR 305

EIF4E Antibody
MBS8580548-01mLAF405L 0.1mL(AF405L)
EUR 465

EIF4E Antibody
MBS8580548-01mLAF405S 0.1mL(AF405S)
EUR 465

EIF4E Antibody
MBS8580548-01mLAF610 0.1mL(AF610)
EUR 465

EIF4E Antibody
MBS8580548-01mLAF635 0.1mL(AF635)
EUR 465

eIF4E Antibody
PHY6313A 150 μg
EUR 318

EIF4E Antibody
MBS9607538-01mL 0.1mL
EUR 260

EIF4E Antibody
MBS9607538-02mL 0.2mL
EUR 305

EIF4E Antibody
MBS9607538-5x02mL 5x0.2mL
EUR 1220

EIF4E Antibody
MBS9601736-01mL 0.1mL
EUR 260

EIF4E Antibody
MBS9601736-02mL 0.2mL
EUR 305

EIF4E Antibody
MBS9601736-5x02mL 5x0.2mL
EUR 1220

EIF4E Antibody
MBS9602521-005mL 0.05mL
EUR 260

EIF4E Antibody
MBS9602521-01mL 0.1mL
EUR 325

EIF4E Antibody
MBS9602521-02mL 0.2mL
EUR 400

EIF4E Antibody
MBS9602521-5x02mL 5x0.2mL
EUR 1750

EIF4E Antibody
MBS9406517-005mL 0.05mL
EUR 300

EIF4E Antibody
MBS9406517-01mL 0.1mL
EUR 390

EIF4E Antibody
MBS9406517-5x01mL 5x0.1mL
EUR 1610

eIF4E Antibody
MBS9504119-005mL 0.05mL
EUR 285

eIF4E Antibody
MBS9504119-01mL 0.1mL
EUR 385

eIF4E Antibody
MBS9504119-5x01mL 5x0.1mL
EUR 1590

eIF4E Antibody
MBS9613762-01mL 0.1mL
EUR 260

eIF4E Antibody
MBS9613762-02mL 0.2mL
EUR 305

eIF4E Antibody
MBS9613762-5x02mL 5x0.2mL
EUR 1220

eIF4E Antibody
MBS9610990-005mL 0.05mL
EUR 245

eIF4E Antibody
MBS9610990-01mL 0.1mL
EUR 305

eIF4E Antibody
MBS9610990-02mL 0.2mL
EUR 365

eIF4E Antibody
MBS9610990-5x02mL 5x0.2mL
EUR 1495

eIF4E-IN-6
HY-155337 Get quote Ask for price
Description: eIF4E-IN-6(compound 4b) is a GMP analogs synthesized to targeteIF4Eand restrain its binding to cap mRNA.eIF4E-IN-6shows cell cytotoxicity against Caco-2, HepG-2,and MCF-7 cells, withIC50values of 31, 27, and 21 μM, respectively[1].

eIF4E-IN-5
HY-155676 Get quote Ask for price
Description: eIF4E-IN-5 (Compound 6n) is a eIF4E cell-permeable inhibitor. eIF4E-IN-5 can bind to capped mRNA to inhibit cap-dependent translation[1].

eIF4E-IN-1
HY-145240 Get quote Ask for price
Description: eIF4E-IN-1 is a potent inhibitor of eIF4E. eIF4E-IN-1 inhibits immunosuppression components such as immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immune suppression in certain diseases, such as cancer and infectious disease (extracted from patent WO2021003194A1, compound Y)[1].

eIF4E-IN-2
HY-145262 Get quote Ask for price
Description: eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e). eIF4E-IN-2 has the potential for researching eIF4e dependent diseases, including the research of cancer (extracted from patent WO2021003157A1, compound 1188)[1]. eIF4E-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

eIF4E-IN-3
HY-145309 Get quote Ask for price
Description: eIF4E-IN-3 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e). eIF4E-IN-3 has the potential for researching eIF4e dependent diseases, including the research of cancer (extracted from patent WO2021003157A1, compound 485)[1].

eIF4E-IN-3
MBS5800494-5mg 5(mg
EUR 915

eIF4E-IN-3
MBS5800494-5x5mg 5x5(mg
EUR 3970

eIF4E-IN-1
MBS5800495-5mg 5(mg
EUR 915

eIF4E-IN-1
MBS5800495-5x5mg 5x5(mg
EUR 3970

eIF4E-IN-2
MBS5800498-5mg 5(mg
EUR 915

eIF4E-IN-2
MBS5800498-5x5mg 5x5(mg
EUR 3970

eIF4E-IN-3
T40210-10mg 10mg Ask for price
Description: eIF4E-IN-3

eIF4E-IN-3
T40210-1g 1g Ask for price
Description: eIF4E-IN-3

eIF4E-IN-3
T40210-1mg 1mg Ask for price
Description: eIF4E-IN-3

eIF4E-IN-3
T40210-50mg 50mg Ask for price
Description: eIF4E-IN-3

eIF4E-IN-3
T40210-5mg 5mg Ask for price
Description: eIF4E-IN-3

eIF4E-IN-1
T40211-10mg 10mg Ask for price
Description: eIF4E-IN-1

eIF4E-IN-1
T40211-1g 1g Ask for price
Description: eIF4E-IN-1

eIF4E-IN-1
T40211-1mg 1mg Ask for price
Description: eIF4E-IN-1

eIF4E-IN-1
T40211-50mg 50mg Ask for price
Description: eIF4E-IN-1

eIF4E-IN-1
T40211-5mg 5mg Ask for price
Description: eIF4E-IN-1

eIF4E-IN-2
T40214-10mg 10mg Ask for price
Description: eIF4E-IN-2

eIF4E-IN-2
T40214-1g 1g Ask for price
Description: eIF4E-IN-2

eIF4E-IN-2
T40214-1mg 1mg Ask for price
Description: eIF4E-IN-2

eIF4E-IN-2
T40214-50mg 50mg Ask for price
Description: eIF4E-IN-2

eIF4E-IN-2
T40214-5mg 5mg Ask for price
Description: eIF4E-IN-2

eIF4E Mouse mAb
A0467 100μL
EUR 262.15

eIF4E, GST-tag
40530 100 µg
EUR 425
Description: Human eIF4e (eukaryotic translation initiation factor 4E) (GenBank Accession No. NM_001968), a.a. 2-216 with N-terminal GST-tag, MW= 51 kDa, expressed in an E. coli expression system.

Rat EIF4E siRNA
20-abx915211
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

EIF4E Mouse mAb
E2222620 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

EIF4E Mouse mAb
E2620407 100ul
EUR 225
Description: Available in various conjugation types.

EIF4E Mouse mAb
E2600167 100ul
EUR 225
Description: Available in various conjugation types.

EIF4E siRNA (Rat)
MBS8212162-15nmol 15nmol
EUR 405

EIF4E siRNA (Rat)
MBS8212162-30nmol 30nmol
EUR 565

EIF4E siRNA (Rat)
MBS8212162-5x30nmol 5x30nmol
EUR 2450

EIF4E Mouse mAb
MBS8550757-01mL 0.1mL
EUR 305

EIF4E Mouse mAb
MBS8550757-01mLAF405L 0.1mL(AF405L)
EUR 565

EIF4E Mouse mAb
MBS8550757-01mLAF405S 0.1mL(AF405S)
EUR 565

EIF4E Mouse mAb
MBS8550757-01mLAF610 0.1mL(AF610)
EUR 565

EIF4E Mouse mAb
MBS8550757-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E Mouse mAb
MBS8558662-01mL 0.1mL
EUR 305

EIF4E Mouse mAb
MBS8558662-01mLAF405L 0.1mL(AF405L)
EUR 565

EIF4E Mouse mAb
MBS8558662-01mLAF405S 0.1mL(AF405S)
EUR 565

EIF4E Mouse mAb
MBS8558662-01mLAF610 0.1mL(AF610)
EUR 565

EIF4E Mouse mAb
MBS8558662-01mLAF635 0.1mL(AF635)
EUR 565

EIF4E Rabbit pAb
A2162-100ul 100 ul
EUR 369.6

EIF4E Rabbit pAb
A2162-200ul 200 ul
EUR 550.8

EIF4E Rabbit pAb
A2162-20ul 20 ul
EUR 219.6

EIF4E Rabbit pAb
A2162-50ul 50 ul
EUR 267.6

eIF4E Rabbit pAb
A0468 200μL
EUR 623.48

EIF4E Rabbit pAb
A0468-200ul 200 ul
EUR 550.8

EIF4E Rabbit pAb
A0468-20ul 20 ul
EUR 219.6

eIF4E Rabbit mAb
A19044 500μL
EUR 1657.89
Description: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human Ezrin (P15311).

EIF4E Rabbit mAb
A19044-100ul 100 ul
EUR 492

EIF4E Rabbit mAb
A19044-200ul 200 ul
EUR 685.2

EIF4E Rabbit mAb
A19044-20ul 20 ul
EUR 265.2

A novel utility of MD following with the dynamical cross-correlation matrix (DCCM) evaluation instrument was used to determine putative protein domains to substantiate the steadiness of the expected mannequin and investigated the distinction of their dynamical conduct with the correlative fluctuations in movement.C-score in sufficient vary, the obtained fashions confirmed extra reliability.

The organic interpretation of the Viral Protein 2 of BTV was predicted DCCM maps had been calculated, every utilizing a unique coordinate reference body from which protein area boundaries and protein area residue constituents could possibly be recognized. Moreover, we anticipated that this analysis to play a promising function identification of novel candidate with the goal protein to inhibit their purposeful significance.